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Original Articles
- Relationship between sonorheometry parameters and laboratory values in a critical care setting in Italy: a retrospective cohort study
- Antonio Romanelli, Renato Gammaldi, Alessandro Calicchio, Salvatore Palmese, Antonio Siglioccolo
- J Trauma Inj. 2023;36(3):210-216. Published online July 4, 2023
- DOI: https://doi.org/10.20408/jti.2023.0014
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Abstract
PDF - Purpose
This preliminary retrospective study analyzed the relationship between the parameters provided by sonorheometry device Quantra and the coagulation values obtained from standard venous blood samples in patients admitted in intensive care unit (ICU).
Methods
We reviewed medical charts of 13 ICU adult patients in whom at least one coagulation study with Quantra was performed. The relationship between Quantra and laboratory data was analyzed with the Spearman rank correlation coefficient (rho). The 95% confidence interval (CI) was computed. A P-value <0.05 was considered statistically significant.
Results
We collected 28 data pairs. Statistically significant moderate correlations were found for the following parameters: clot time (CT) and activated partial thromboplastin time (rho=0.516; 95% CI, 0.123–0.904; P=0.009; clot stiffness (CS) and the international normalized ratio (INR; rho=0.418; 95% CI, 0.042–0.787; P=0.039); INR and platelet contribution to CS (rho=0.459; 95% CI, 0.077–0.836; P=0.022); platelet count and platelet contribution to CS (PCS; rho=0.498; 95% CI, 0.166–0.825; P=0.008); and fibrinogen and fibrinogen contribution to CS (FCS; rho=0.620; 95% CI, 0.081–0.881; P=0.001).
Conclusions
Quantra can provide useful information regarding coagulation status, showing modest correlations with the parameters obtained from laboratory tests. During diffuse bleeding, CT and FCS values can guide the proper administration of clotting factors and fibrinogens. However, the correlation of INR with CS and PCS can cause misinterpretation. Further studies are needed to clarify the relationship between Quantra parameters and laboratory tests in the critical care setting and the role of sonorheometry in guiding targeted therapies and improving outcomes. -
Summary
- Sports injuries: a 5-year review of admissions at a major trauma center in the United Kingdom
- Ahmad Hammad Hassan, Aref-Ali Gharooni, Harry Mee, James Geffner, Fahim Anwar
- J Trauma Inj. 2023;36(1):39-48. Published online July 14, 2022
- DOI: https://doi.org/10.20408/jti.2021.0084
- 3,128 View
- 55 Download
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Abstract
PDF
- Purpose
Sports offer several health benefits but are not free of injury risk. Activity dynamics vary across sports, impacting the injury profile and thereby influencing healthcare resource utilization and health outcomes. The purpose of this study was to investigate sports-related major trauma cases and compare differences across sports and activity groups.
Methods
A retrospective case notes review of sports-related major traumas over a 5-year period was conducted. Demographic, hospital episode-related, and health outcome-related data were analyzed, and differences were compared across sports and activity groups. The Glasgow Outcome Scale (GOS) at discharge was used as the primary outcome measure and the length of hospital stay as the secondary outcome measure.
Results
In total, 74.6% of cases had good recovery at discharge (GOS, 5), 18.9% had moderate disability (GOS, 4), and 3.7% had severe disability (GOS, 3). The mean length of hospital stay was 11.2 days (range, 1–121 days). The most severely injured body region was the limbs (29.1%) and vertebral/spinal injuries were most common in terms of location (51.8%). A significant difference (P<0.05) existed in GOS across sports groups, with motor sports having the lowest GOS. However, no significant differences (P>0.05) were found in other health-outcome variables or injury patterns across sports or activity groups, although more competitive sports cases (67.08%) required admission than recreational sports cases (32.9%).
Conclusions
Spinal injuries are the most frequent sports injuries, bear the worst health outcomes, and warrant better preventive measures. Head injuries previously dominated the worst outcomes; this change is likely due to better preventive and management modalities. Competitive sports had a higher injury frequency than recreational sports, but no difference in health outcomes or injury patterns. -
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