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Case Reports
Cerebral Fat Embolism That Was Initially Negative on DiffusionWeighted Magnetic Resonance Imaging
Seung Je Go, Yun Su Mun, Seung Ho Bang, Yong Han Cha, Young Hoon Sul, Jin Bong Ye, Jae Guk Kim
J Trauma Inj. 2021;34(2):126-129.   Published online March 22, 2021
DOI: https://doi.org/10.20408/jti.2020.0007
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AbstractAbstract PDF

Fat embolism syndrome is a rare, but serious condition that occurs in patients with fractures of the long bones or who undergo orthopedic surgery. The main clinical features of fat embolism syndrome are an altered mental status, hypoxia, and petechial rash. Cerebral fat embolism is the most severe manifestation of fat embolism syndrome because it can lead to an altered mental status. The diagnosis of cerebral fat embolism is clinical, but brain magnetic resonance image (MRI) is helpful. There is usually an interval until symptoms, such as an altered mental status, develop after trauma. We report a case of cerebral fat embolism in which the patient’s mental status deteriorated several hours after trauma and the initial findings were negative on diffusion-weighted MRI.

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Fat Embolism Syndrome - Three Case Reports and Review of the Literature
Leonidas Grigorakos, Ioannis Nikolopoulos, Stamatina Stratouli, Anastasia Alexopoulou, Eleftherios Nikolaidis, Eleftherios Fotiou, Daria Lazarescu, Ioannis Alamanos
J Trauma Inj. 2017;30(3):107-111.   Published online October 30, 2017
DOI: https://doi.org/10.20408/jti.2017.30.3.107
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  • 2 Citations
AbstractAbstract PDF
The fat embolism syndrome (FES) represents a condition, usually with traumatic etiology, which may pose challenges to diagnosis while its treatment usually requires supportive measures in the intensive care units (ICUs). The clinical criteria, including respiratory and cerebral dysfunction and a petechial rash, along with imaging studies help in diagnosis. Here we present three case reports of young male who developed FES and were admitted to our ICUs after long bones fractures emerging after vehicle crashes and we briefly review FES literature. All patients' treatment was directed towards: 1) the restoration of circulating volume with fresh blood and/or plasma; 2) the correction of acidosis; and 3) immobilization of the affected part. All patients recovered and were released to the orthopedic wards. The incidence of cases of patients with FES admitted in our ICUs records a significant decrease. This may be explained in terms effective infrastructure reforms in Greece which brought about significant improvement in early prevention and management.
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Citations

Citations to this article as recorded by  
  • Fat embolism mimicking pulmonary embolism: A case report
    Chathuri Munagama, Rasanee Wanigasuriya, Arul Kumaran, Thushara Matthias
    SAGE Open Medical Case Reports.2024;[Epub]     CrossRef
  • Late-onset isolated cerebral fat embolism syndrome after a simple tibial plateau fracture: a rare case report
    Ta-Li Hsu, Tien-Chi Li, Fei-Pi Lai, Ming Ouhyoung, Chih-Hung Chang, Cheng-Tzu Wang
    Journal of International Medical Research.2021;[Epub]     CrossRef

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